If you’re unsure whether to choose the ResMed AirSense 10 vs 11, this article will help make your decision easier. CLM Sleep provides detailed insights into the features, compatibility, and ideal users for each model. We’ll also highlight the key differences and notable improvements of the AirSense 11 AutoSet over the AirSense 10 AutoSet. Let’s explore which option best fits your therapy needs and lifestyle.
ResMed AirSense 10 Autoset
Launched in 2014, the AirSense 10 AutoSet is a CPAP machine designed to automatically adjust pressure according to nightly respiratory needs, optimizing treatment effectiveness while ensuring comfort. Compared to the previous S9 autoset line, the AirSense 10 has made significant improvements such as integrating the HumidAir humidifier directly into the machine body and the ability to connect wirelessly to send treatment data directly to the doctor through the AirView system.

Key features
- AutoSet™: Automatically adjusts pressure throughout the night, providing personalized therapy.
- HumidAir™: integrates the HumidAir humidifier directly into the machine body, helping to reduce nasal and throat dryness, increasing comfort.
- Easy-Breathe technology: Simulates natural breathing rhythms to enhance comfort during inhalation and exhalation.
- Exhalation pressure relief (EPR™) technology: Reduce pressure when exhaling
- Wireless connection: Support for remote monitoring and adjustment via AirView.
- User-friendly interface with a color screen and ambient light sensor.
- SmartStart™ function: Starts treatment when you wear the mask and automatically stops when you remove it.
- Operates quietly, no noise while sleeping.
Compatibility
- Compatible with all types of Resmed masks (Nasal, Full Face, Pillow)
- Compatible with ClimateLineAir™ tubing
Who is it for?
AirSense 10 AutoSet will be the ideal choice for
- Those who are new to CPAP therapy
- Those who need stable therapy at home
- Patients with mild to moderate sleep apnea.
ResMed AirSense 11 Autoset
Launched in 2021, the AirSense 11 AutoSet is a comprehensive upgrade of the AirSense 10 line, designed to provide a more personalized and modern treatment experience. Compared to the AirSense 10, this new version also improves data collection and transmission capabilities, providing maximum support for remote monitoring and timely adjustment of treatment plans.

What’s New in AirSense 11
Standard AutoSet and AutoSet for Her: With the AirSense 10, users needed to choose between the AutoSet and AutoSet for Her models. However, the AirSense 11 AutoSet now integrates both algorithms in a single device
Touchscreen: Replaces the traditional rotary knob, faster, more modern, and easier to operate.
Care Check-In: Personalized guidance for new users, tracking progress, and providing appropriate advice.
Over-the-air updates: The device is always updated without manual intervention.
Compatibility
- Mask: Compatible with most types of masks, including the latest mask line
- HumidAir: ClimateLineAir 11 tube (new)
- Software: Supports AirView, myAir (fully featured, with Care Check-In)
- Not compatible with the power supply or some accessories of AirSense 10
Who is it for?
AirSense 11 AutoSet is the right choice for
- those who are just starting CPAP therapy,
- those who want a modern, easy-to-use device or are tech-savvy,
- and those who prioritise self-monitoring and smart, flexible treatment adaptation.
Head-to-Head Comparison: ResMed AirSense 10 vs 11
To help you decide which CPAP machine best suits your needs, here’s a side-by-side comparison of the ResMed AirSense 10 AutoSet and AirSense 11 AutoSet. This table highlights the key features, compatibility, and user suitability of each model.
Product features and specifications | AirSense 10 AutoSet | AirSense 11 AutoSet |
Weight | 1428 g | 1130 g |
AutoRamp with sleep onset detection | ✓ | ✓ |
Display | Button + screen | Full touchscreen |
Noise | 27 dBA | 27 dBA |
SmartStart/Stop feature | ✓ | ✓ |
Test Drive | Not included | ✓ |
Personal Therapy Assistant | Not included | ✓ |
Care Check-In | Not included | ✓ |
OTA: over-the-air software updates* | Not included | ✓ |
myAir | ✓ | ✓ |
Supplemental oxygen use | Up to 4L/min | Up to 15L/min |
AutoSet for Her algorithm | Not included | ✓ |
Bluetooth connectivity | Not included | ✓ |
Built-in cellular technology* | ✓ | ✓ |
Humidification (standard fully integrated) | ✓ | ✓ |
Price | $1,288 (with mask) | $1,695 (with mask) |
Note: Prices referenced from CLM Sleep and CPAP Discount.
Conclusion
Choosing between the ResMed AirSense 10 and AirSense 11 depends on personal needs, budget, and the level of technological support you desire during treatment. No matter which version you choose, both models provide high treatment efficacy for sleep apnea. If you are still unsure, don’t hesitate to contact the team of experts at CLM Sleep for free and personalized consultation according to your treatment needs.